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KMID : 0870519980020020149
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Journal of Korean Academy of Addiction Psychiatry
1998 Volume.2 No. 2 p.149 ~ p.155
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Pharmacotherapy of Alcohol Dependence-Drugs Mainly Acting on the Opiod Systim
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Kim Sung-Gon
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Abstract
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Naltrexone is approved by FDA for the treatment of alcoholism at 1994. After then, the concern about central opioid
system in alcoholism has been markedly increased. In the first part of this paper, the author reviewed the papers about
treatment efficacy and mechanism, pharmacology, and clinical use of naltrexone in alcoholism. In the second part, the papers about the treatment efficacy of other opioid receptor antagonists in alcoholism were reviewed.
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KEYWORD
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Alcoholism, Opioid system, Naltrexone
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